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The researchers behind peptide science.

Meet researchers whose published work helped define MOTS-c, SS-31, and glucagon-like peptide biology.

Portrait of Pinchas Cohen, MD
Leonard Davis School of Gerontology

Pinchas Cohen, MD

Distinguished Professor and Dean

MOTS-c · Mitochondrial-derived peptides

“MOTS-c treatment in mice prevented age-dependent and high-fat-diet-induced insulin resistance, as well as diet-induced obesity.”

2015 preclinical mouse study
Portrait of Hazel H. Szeto, MD, PhD
Weill Cornell Medicine

Hazel H. Szeto, MD, PhD

Pharmacologist and peptide researcher

SS-31 · Mitochondrial peptide biology

“SS-31 is a mitochondria-targeted tetrapeptide that can scavenge mitochondrial ROS and inhibit MPT…”

2011 preclinical rat study
Portrait of Daniel J. Drucker, MD
University of Toronto · Sinai Health

Daniel J. Drucker, MD

University Professor and clinician-scientist

GLP-1 and GLP-2 · Regulatory peptides

“Glucagon-like peptide-1 (GLP-1) released from gut enteroendocrine cells controls meal-related glycemic excursions through augmentation of insulin and inhibition of glucagon secretion.”

2018 peer-reviewed review
Portrait of Jens Juul Holst, MD, DMSc
University of Copenhagen

Jens Juul Holst, MD, DMSc

Professor of Medical Physiology

GIP and GLP-1 · Incretin physiology

“The incretin effect … is one of the factors that help the body to tolerate carbohydrate/glucose ingestion.”

2019 peer-reviewed review

Independent research, presented for scientific context. These researchers and institutions are not affiliated with Peptyed and do not endorse its products.

Pinchas Cohen, MD

Distinguished Professor and Dean

USC Leonard Davis School of Gerontology

Cohen and collaborators reported MOTS-c, a mitochondrial-encoded 16-amino-acid peptide, and studied its role in metabolic homeostasis.

2015 preclinical mouse study

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

This publication is presented for scientific context. The researcher and institution are not affiliated with Peptyed and do not endorse Peptyed products.

Photo: USC Leonard Davis School of Gerontology

Hazel H. Szeto, MD, PhD

Pharmacologist and peptide researcher

Weill Cornell Medicine

Szeto led foundational work on SS-31, a mitochondria-targeted tetrapeptide, and its behavior in ischemia-reperfusion models.

2011 preclinical rat study

Mitochondria-targeted peptide accelerates ATP recovery and reduces ischemic kidney injury

This publication is presented for scientific context. The researcher and institution are not affiliated with Peptyed and do not endorse Peptyed products.

Photo: John Abbott / Weill Cornell Medicine

Daniel J. Drucker, MD

University Professor and clinician-scientist

University of Toronto · Sinai Health

Drucker’s research helped define GLP-1 and GLP-2 biology and the mechanisms of glucagon-like peptide action.

2018 peer-reviewed review

Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1

This publication is presented for scientific context. The researcher and institution are not affiliated with Peptyed and do not endorse Peptyed products.

Photo: Brigitte Lacombe / Breakthrough Prize

Jens Juul Holst, MD, DMSc

Professor of Medical Physiology

University of Copenhagen

Holst’s work has helped explain the incretin effect and the physiology of GIP and GLP-1.

2019 peer-reviewed review

The incretin system in healthy humans: The role of GIP and GLP-1

This publication is presented for scientific context. The researcher and institution are not affiliated with Peptyed and do not endorse Peptyed products.

Photo: Brigitte Lacombe / Breakthrough Prize

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